The estimated market size of the Global Hyperimmune Globulins is expected to reach USD billion in revenue, with a significant Compound Annual Growth Rate (CAGR) of anticipated through 2027. The surge in global deadly disease outbreaks is a primary driver of market growth. Hyperimmune globulins, utilized to treat active infections in immunosuppressed hosts, resemble Intravenous Immunoglobulins (IVIGs) but are derived from donors with high antibody titers against specific antigens or organisms. These donors have either been naturally infected or exposed to the disease or artificially immunized.

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Hyperimmune globulin administration confers passive immunity against specific agents, providing immediate but short-term protection compared to the active immunity offered by IVIGs. Hyperimmune globulins are crucial for diseases like rabies, hepatitis B, varicella-zoster, and tetanus toxin, offering quick, short-lived immunity. In cases where patients cannot synthesize antibodies, have contracted a disease, or lack an adequate immune response, hyperimmune globulins play a vital role.

In the United States, nearly 380 certified International Quality Plasma Program and FDA-licensed plasma collection centers, predominantly owned by plasma therapy manufacturers, contribute to frequent plasma donations. An increase in voluntary plasma donation and the occurrence of disease outbreaks like SARS, MERS, COVID-19, among others, are expected to positively impact the global hyperimmune globulins market until 2027.

Despite the desirability of human hyperimmune globulins, extensive usage faces challenges due to costly donor screening protocols and the potential transmission of unidentified pathogens. Serious side effects in some cases also contribute to industry growth concerns.

The market is segmented based on product types (hepatitis B, tetanus, rabies, Rhо (D), and others), end-use (government institutions, private sector, and others), and regionally, with North America and Europe anticipated to be key contributors to market share.

Key players in the global hyperimmune globulins market include Hualan Bio, Shanghai RAAS, CSL Behring, Grifols, Biotest, CNBG, CBPO, Sichuan Yuanda Shuyang, Emergent (Cangene), ADMA Biologics, Kedrion, and Kamada. Industry players are adopting strategies like acquisitions, mergers, collaborations, and capacity expansion to foster market growth, with significant investments in R&D activities.

Notably, in March 2020, Grifols collaborated with US BARDA, FDA, and other federal health agencies to develop a plasma-derived COVID-19 drug. Additionally, Kleo Pharmaceuticals received a USD 5 million grant from the Bill & Melinda Gates Foundation in July 2020 to advance its coronavirus treatment using Monoclonal Antibody Therapy Enhancers (MATE™) technology. The report provides a comprehensive analysis of the global hyperimmune globulins market, forecasting revenue growth globally, regionally, and at the country level from 2017 to 2027.

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